Volume : 9
Issue : 1
A retrospective study of antimicrobial susceptibility pattern of aerobic microbial isolates from urine samples of patients attending a tertiary care hospital
Ahmad S, Jahan N, Ahmad SS, Singh N, Khatoon R
Pdf Page Numbers :- 5-10
Siraj Ahmad1, Noor Jahan2, Syed Saif Ahmad3, Nidhi Singh2,* and Razia Khatoon4
1Department of Community Medicine, Integral Institute of Medical Sciences & Research, Integral University, Lucknow- 226026, UP, India
2Department of Microbiology, Integral Institute of Medical Sciences and Research, Lucknow-226026, UP, India
3Charak Diagnostics Centre, Chowk, Lucknow-226003, UP, India
4Department of Microbiology, Hind Institute of Medical Sciences, Mau, Ataria, Sitapur-261303, UP, India
*Corresponding author: Miss. Nidhi Singh, Department of Microbiology, Integral Institute of Medical Sciences & Research, Integral University, Lucknow-226026, U.P., India. Email: Singhnidhi892@yahoo.com
Received 9 September 2020; Revised 25 November 2020; Accepted 8 December 2020; Published 22 December 2020
Citation: Ahmad S, Jahan N, Ahmad SS, Singh N, Khatoon R. A retrospective study of antimicrobial susceptibility pattern of aerobic microbial isolates from urine samples of patients attending a tertiary care hospital. J Med Sci Res. 2021; 9(1):5-10. DOI: http://dx.doi.org/10.17727/JMSR.2021/9-2
Copyright: © 2021 Ahmad S et al. Published by KIMS Foundation and Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Background: Urinary tract infections (UTIs) are one of the most common infections encountered in clinical practice.
Objective: This is a retrospective study to evaluate the antimicrobial susceptibility pattern of aerobic microbial isolates from urine samples of patients with complaints suggestive of UTI.
Materials and methods: A total of 3116 urine samples which were received in the Department of Microbiology during the study period from April 2018 to March 2019 were analyzed.
Results: Out of 3116 urine samples from both outpatient (OPD) and inpatient department (IPD), 2614 samples showed either growth of contaminants or insignificant or no growth of microorganisms, whereas, 502 samples showed significant microbial growth on aerobic culture giving overall prevalence of UTI in the study population to be 16.1%. Of these 502 culture positives, majority was found to be from OPD (51.0%) patients, amongst females (62.9%), and Escherichia coli being the commonest isolate (49.8%). The antibiotic sensitivity of uroisolates of Escherichia coli were found to range from 46.0-70.0%.
Conclusion: In view of the increasing drug resistance amongst pathogens causing UTI, antimicrobial susceptibility should be done before initiating definitive therapy. These data may be used to formulate local antibiotic policies in order to assist clinicians in the rationale use of antibiotics.
Keywords: aerobic microbial isolates; urinary tract infection; antimicrobial susceptibility test; retrospective analysis.