Volume : 8
Issue : S1
A review on importance of biochemical markers in coronavirus disease (COVID-19)
Lagisetty L, Darapuneni RC
Pdf Page Numbers :- 53-58
Lavanya Lagisetty1,*, Radhika Chowdary Darapuneni1
1Department Laboratory Medicine, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003.Telangana, India
*Corresponding author: Dr. Lavanya Lagisetty, MD (Biochemistry), Department Laboratory Medicine, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, India. Email: email@example.com
Received 15 September 2020; Revised 2 November 2020; Accepted 11 November 2020; Published 19 November 2020
Citation: Lagisetty L, Darapuneni RC. A review on importance of biochemical markers in coronavirus disease (COVID-19). J Med Sci Res. 2020; 8(S1):53-58. DOI: http://dx.doi.org/10.17727/JMSR.2020/8S1-6
Copyright: © 2020 Lagisetty L et al. Published by KIMS Foundation and Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) is the pathogen responsible for the corona virus disease 2019 (COVID-19) pandemic. The disease mainly affects the respiratory system of the patient, in particular, the lungs, presenting with acute respiratory distress syndrome and acute respiratory failure. Laboratory findings are adding importance in diagnosis, prognosis and treatment of COVID. The biochemical parameters are altered based on severity of the disease and its complications. D-dimer and LDL are commonly elevated in patients with COVID-19 and are reliable prognostic markers for in-hospital mortality in patients admitted for COVID-19. Hyperferritinemia and disease severity in patients with COVID-19 is positively correlated. It is said that the detrimental effects on liver injury were related to certain medications used during hospitalization, which warrants frequent monitoring and evaluation for these patients. SARS-CoV-2 affects the patients with COVID-19 in aspects of direct infection of myocardial injury, specific binding to functional receptors on cardiomyocytes, and immune-mediated myocardial injury. Therefore, early, simple and effective diagnosis of severe COVID-19 pneumonia is of great significance in reducing mortality and shortening the hospitalization period.
Keywords: SARS- CoV-2; COVID 19; pneumonia; inflammatory markers