Volume : 10
Issue : 1
A study of microbiology in diabetic foot infections
Karvande RK, Merchant T, Shinde PH, Takalkar YP, Chaudhari S, Chakravarthy V, Deshmukh VK, Admane K
Pdf Page Numbers :- 20-24
Rajiv K Karvande1, Taher Merchant2, Pravin H Shinde1, Yogesh P Takalkar1,*, Sadashiv Chaudhari1, Vaishnavi Chakravarthy1, Virendra Kumar Deshmukh1, and Karan Admane1
1Department of General Surgery, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra-400012, India
2Department of General Surgery, Rajawadi Hospital, Mumbai, Maharashtra-400077, India
*Corresponding author: Dr. Yogesh P Takalkar, Assistant Professor, Department of General Surgery, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra-400012, India. Mobile: 8976606005; Email: firstname.lastname@example.org
Received 15 September 2021; Revised 24 November 2021; Accepted 7 December 2021; Published 16 December 2021
Citation: Karvande RK, Merchant T, Shinde PH, Takalkar YP, Chaudhari S, Chakravarthy V, Deshmukh VK, Admane K. A study of microbiology in diabetic foot infections. J Med Sci Res. 2022; 10(1):20-24. DOI: http://dx.doi.org/10.17727/JMSR.2022/10-5
Copyright: © 2022 Karvande RK et al. Published by KIMS Foundation and Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Background: Diabetic foot ulcers and infections are a common complication of diabetes. Holistic patient care requires dissemination of knowledge about prevention to avoid amputation and associated morbidity, early diagnosis and apt treatment. Healthcare costs of diabetic ulcers are high as complete treatment requires long term monitoring and high cost of rehabilitation in amputees.
Methods: The study design is retrospective observational study. All data was retrospectively procured from the Medical Record Department. From January 2019 to December 2019, two hundred and twenty patients with diabetic foot infections who had been treated with oral or parenteral antibiotics in the previous 5 to 15 days were chosen.
Results: The gram negative bacteria (88%) were most commonly isolated. Gram positive organisms contributed to 11% and candida spp. to 1% of swab culture. All patients with Staphylococci in wound swab were 100% sensitivity to vancomycin & linezolid. Teicoplanin, vancomycin, and clindamycin had 100% sensitivity against MRSA in wound swab. Patients with E. coli in wound swab had maximum sensitivity to colistin. Ceftriaxone which has been used conventionally was found less sensitive for E. coli and Klebsiella.
Conclusion: Piperacillin tazobactam combination for gram negative coverage in accordance to sensitivity pattern of community acquired infection is recommended because conventionally used ceftriaxone is less sensitive. For gram positive diabetic foot ulcers/ infections which were seen to be hospital acquired, linezolid is recommended for full course.
Keywords: diabetes; antibiotics; microbiology; bacteria; foot