Pemphigus and its variants with direct immunofluorescence: Case series of 32 cases

Arundhathi S

Pdf Page Numbers :- 173-177

Arundhathi S^1,*

¹Department of Pathology, All India Institute of Medical Sciences, Mangalagiri, Andhra Pradesh, India

*Corresponding author: Dr. Arundhathi S, Associate Professor, Department of Pathology, All India Institute of Medical Sciences, Old TB Sanatorium Road, Mangalagiri, Andhra Pradesh-522503, India. Mobile: +91 9449670559; Email: arundhathi19@yahoo.co.in

Received 21 April 2021; Revised 31 May 2021; Accepted 11 June 2021; Published 21 June 2021

Citation: Arundhathi S. Pemphigus and its variants with direct immunofluorescence: Case series of 32 cases. J Med Sci Res. 2021; 9(3):173-177. DOI: http://dx.doi.org/10.17727/JMSR.2021/9-25

Copyright: © 2021 Arundhathi S. Published by KIMS Foundation and Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Abstract

Pemphigus is a group of autoimmune vesiculobullous diseases of skin and mucous membrane. Histologically characterised by intraepidermal bulla and immunologically by circulating IgG autoantibodies targeted against keratinocytes. We are presenting 32 cases of pemphigus and its variants. The histopathologic and direct immunofluorescence (DIF) findings are described.

Keywords: pemphigus; direct immunofluorescence; intraepidermal bulla; pemphigus vulgaris.