Efficacy, usage and adverse effects of furosemide in cardiovascular diseases

Palaparthi T, Reddy AU, Poornender AR

Pdf Page Numbers :- 267-269

Twila Palaparthi¹, Upendhar Reddy A^1,* and Rohan Poornender A¹

¹Department of Pharmacy, Bharat Institute of Technology, Jawaharlal Nehru Technological University Hyderabad, Mangalpally, Ibrahimpatnam, Telangana 501510, India

*Corresponding author: Upendhar Reddy A, Department of Pharmacy, Bharat Institute of Technology, Jawaharlal Nehru Technological University Hyderabad, Mangalpally, Ibrahimpatnam, 501510, Telangana, India. Email: upendharreddy0064@gmail.com

Received 26 March 2024; Revised 14 May 2024; Accepted 29 May 2024; Published 5 June 2024

Citation: Palaparthi T, Reddy AU, Poornender AR. Efficacy, usage and adverse effects of furosemide in cardiovascular diseases. J Med Sci Res. 2024; 12(3):267-269. DOI: http://dx.doi.org/10.17727/JMSR.2024/12-50

Copyright: © 2024 Palaparthi T et al. Published by KIMS Foundation and Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Abstract

Cardiovascular diseases can be caused by numerous beginning conditions. The underpinning causes may include heart/ myocardial inflammation, cardio myopathy, coronary vascular complaint (CAD), dyslipidemia, hypertension, pulmonary hypertension, and arrhythmia, which may eventually affect heart and liver failure. The study was aimed to determine the efficacy, usage and adverse effects of furosemide in diseased heart conditions. Furosemide is prescribed in the treatment of various cardiovascular illnesses, including monitoring the effects in various age groups, gender and body weights. Considering all the primary parameters of drug dose and secondary parameters of dose duration and their certain categories, we evaluate the results based on the effectiveness of furosemide. The collected and gathered data is analyzed by the suitable statistical methods (Central tendency methods) like Arithmetic mean. The effectiveness of furosemide is rapid and strong in the age group of 39-69yrs with the sodium levels of 132.8mEq/L and the urine output of 2.23L/day. The drug shows potential adverse effects like Ototoxicity, skin irritations and stomach cramps, in people with existing heart conditions. The usage of furosemide is beneficial in heart patients however some people show some potential adverse effects. The drug poses its potential side effects only when the usage is high or in unauthorized dose and also depends on previously existed disease conditions.

Keywords: furosemide; cardiovascular diseases; heart failure; ototoxicity; skin irritations; arithmetic mean; hepatic failure