Comparative study of fasting lipid profile among non-smokers and smokers

Arulmurugan C, Yatheesh A

Pdf Page Numbers :- 94-99

Arulmurugan C^1,* and Adarsh Yatheesh¹

¹Department of Medicine, Vinayaka Mission’s Kirupananda Variyar Medical College and Hospitals, Chinna Seeragapadi, Salem, Tamilnadu-636308, India

*Corresponding author: Dr. Arulmurugan C. MD., Associate Professor, Department of Medicine, Vinayaka Mission’s Kirupananda Variyar Medical College and Hospitals, Chinna Seeragapadi, Salem, Tamilnadu-636308, India. Mobile: +91 9710919719; Email: dr.arulc@gmail.com

Received 30 March 2019; Revised 25 May 2020; Accepted 5 June 2020; Published 16 June 2020

Citation: Arulmurugan C, Yatheesh A. Comparative study of fasting lipid profile among non-smokers and smokers. J Med Sci Res. 2020; 8(3):94-99. DOI: http://dx.doi.org/10.17727/JMSR.2020/8-13

Copyright: © 2020 Arulmurugan C et al. Published by KIMS Foundation and Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Abstract

Background: Inadequate evidence is found about dyslipidaemia from smoking in India. The jeopardy of dissimilar medical complications is regularly reflected as augmented in the circumstance of cig burning. The pervasiveness amongst countryside and town Indians of beedis and tobacco often gives rise to the occurrence of coronary artery illnesses.

Aim: the study aims to assess the variation of lipid profile and dose-related vicissitudes among the non-smokers and smokers by assessing the number of daily amount of beedis and cigarette’s.

Materials and methods: We performed a cross sectional investigation for a period of one year in our hospital. The participants of this study were mostly of age 15-55 and their BMI is below 25. Patients suffering from medical illness were excluded from the study. Our study included 100 non-smokers and 200 smokers. We conducted a semi-structured interview in a form of questionnaire to collect material about smoking habits and diet. Serum samples were collected upon twelve hours of fasting to estimate the lipid profile. The collected serum was centrifuged and 3 ml of blood kept in a vial for lipid profile estimation.

Results: All the lipid variables except HDL-C were found high among smokers when compared to the non-smokers, while in the smoker group the HDL-C levels were lower than non-smokers and statistically important differences were observed. Likewise, most lipid parameters are favourably associated to the numbers of pack years, with the increase in triglyceride level, total cholesterol levels, LDL, VLDL being statistically important, and a clear negative association between HDL-C and pack years.

Conclusion: The study concluded that there is a variation in lipid variables in the smokers serum such as VLDL, TGs, TC and LDL were elevated and that of reduction in HDL is found. This variability causes adverse cardiovascular events and cerebrovascular disease. Lipid profile should be evaluated in smokers to mitigate the risk of coronary artery and the related disease. They will be briefed on the health risks of smoking. They should be convinced to leave cigarette consumption to healthier lifecycle and embrace better lives.

Keywords: lipid parameters; non-smokers; smokers