Complete hydatidiform mole with a coexistent live fetus in a twin pregnancy

Kashif M Mohiuddin, Chinmayee Ratha, Satish Rao I

Pdf Page Numbers :- 111-114

Kashif M Mohiuddin^1,*, Chinmayee Ratha² and Satish Rao I¹

¹Department of Pathology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, India

²Department of Fetal medicine, Navodaya hospital, PG Road, Secunderabad-500003, Telangana, India

*Corresponding author: Dr. Kashif M Mohiuddin,  Department of Pathology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, India. Tel.: 9848969543; Email: kashifhazim@gmail.com

Received 12 April 2017; Revised 15 June 2017; Accepted 24 June 2017; Published 30 June 2017

Citation: Mohiuddin KM, Ratha C, Satishrao I. Complete hydatidiform mole with a coexistent live fetus in a twin pregnancy. J Med Sci Res. 2017; 5(3):111-114. DOI: http://dx.doi.org/10.17727/JMSR.2017/5-21 

Copyright: © 2017 Mohiuddin KM et al. Published by KIMS Foundation and Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Abstract

Background: The reported incidence of hydatidiform mole with coexisting pregnancy is one in 22 000–100 000 pregnancies, most of them being complete hydatidiform moles (CHM) with a fetus; however, the reported prevalence, for a partial mole with a coexisting fetus is 0.005–0.01% of pregnancies.

Case report: This is a case report of a hydatidiform mole with a coexistent live fetus diagnosed at 18 weeks. After thorough counselling, the pregnancy was continued as per the patient’s desire. The pregnancy was closely monitored with serial Serum β hCG, and ultrasound for fetal growth. An emergency caesarean delivery was done at 30 weeks, due to bleeding per vaginam. A live baby was delivered with near normal Apgar score. The placenta with molar tissue was sent for histopathological examination. The histopathology revealed a complete mole with normal placenta. Her serum β hCG reached normal levels after delivery, and she is now on surveillance. Though the general trend is to terminate pregnancy in twins with coexistent mole in anticipation of complications, under close surveillance, optimal outcomes can be achieved.

Conclusion: The option of continuing a twin pregnancy with a complete mole is acceptable. However a close surveillance is required to detect potential early signs of complications. Histopathological examination is essential in distinguishing between partial and complete mole and/or with ancillary studies.

Keywords: complete hydatidiform mole; twin pregnancy; partial mole; trophoblast; hydatidiform mole