Correlation of 30 consecutive idiopathic pulmonary fibrosis patients intertiary care center

Asmath Qureshi, Latha Sarma, Vijayalakshmi Adepu, Nandan Putti, Kapil Alias Mohit Chilana

Pdf Page Numbers :- 157-161

Asmath Qureshi^1,*, Latha Sarma^1,*, Vijayalakshmi Adepu¹, Nandan Putti¹ and Kapil Alias Mohit Chilana¹

¹Department of Pulmonology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, India

*Corresponding authors: Asmath Qureshi, Department of Pulmonology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, India, Tel.:+919866769827; Email: asmathqureshi@gmail.com and Dr. Latha Sarma, Critical respiratory & Sleep specialist, Department of Pulmonology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, India, Email: dr.lathasarma@gmail.com

Received 15 July 2015; Revised 19 September 2015; Accepted 24 September 2015; Published  30 September 2015

Citation: Asmath Qureshi, Latha Sarma, Vijayalakshmi Adepu, Nandan Putti, Mohit Chilana KA. Correlation of 30 consecutive idiopathic pulmonary fibrosis patients intertiary care center. J Med Sci Res. 2015; 3(4):157-161. DOI: http://dx.doi.org/10.17727/JMSR.2015/3-030

Copyright: © 2015 Asmath Qureshi, et al. Published by KIMS Foundation and Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Abstract

Background: Idiopathic pulmonary fibrosis (IPF) is a specific form of chronic, progressive fibrosing interstitial pneumonia of unknown cause, primarily occurring in older adults, limited to the lungs, and associated with histological and/ or radiologic pattern of usual interstitial pneumonia. The objective of the study is to correlate severity of IPF and duration of symptoms with spirometry test/ forced vital capacity (FVC), high resolution computed tomography (HRCT) findings, smoking history, age and sex of 30 consecutive IPF patients in a tertiary care centre.

Methodology: The study was done on 30 consecutive patients of IPF, clinically and radiologically fulfilling the criteria for IPF.

Results: The study group showed significant male predominance of 80%. Subpleural, basal predominance, reticulations and honey-combing pattern on HRCT was seen in 100%, while traction bronchiectasis in 76.7% and minimal ground glassing in 33.3%. 23 out of 30 patients presented with symptom duration of 13-18 months, with mean duration of 16.4 months. 53.3% of the study population were smokers, 26.6% ex-smokers.

Conclusion: Clinicians should integrate clinical, radiological and/ or pathological data to support the diagnosis of IPF. Smokers are at particular risk for IPF and should be watched for at every visit. As IPF evolves over a period of time, early CT chest may not have all the radiological features supporting IPF. Close follow up is therefore suggested.

Keywords: Idiopathic pulmonary fibrosis; Forced vital capacity; High resolution computed tomography; Bronchiectasis