Original Research
2018 June
Volume : 6 Issue : 2

Prevalence and antibiogram of Pseudomonas aeruginosa isolated from various clinical samples in a tertiary care ICU setting

Sukrutha Gopal Reddy, Anil Kumar Bilolikar, Prasanna Lakshmi Kakarla, Udayasree B

Pdf Page Numbers :- 44-48

Sukrutha Gopal Reddy1,*, Anil Kumar Bilolikar1, Prasanna Lakshmi Kakarla1 and Udayasree B1


1Department of Microbiology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, India


*Corresponding author: Dr. Sukrutha Gopal Reddy, Consultant Microbiologist, Krishna Institute of Medical Sciences Ltd, Minister Road, Secunderabad – 500003, Telangana State, India. Mobile: 9177111719; Email: sukruthagopalreddy@gmail.com


Received 31 January 2018; Revised 09 March 2018; Accepted 17 March 2018; Published 23 March 2018


Citation: Reddy SG, Bilolikar AK, Kakarla PL, Udayasree B. Prevalence and antibiogram of Pseudomonas aeruginosa isolated from various clinical samples in a tertiary care ICU setting. J Med Sci Res. 2018; 6(2):44-48. DOI: http://dx.doi.org/10.17727/JMSR.2018/6-8


Copyright: © 2018 Reddy SG et al. Published by KIMS Foundation and Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Background: Pseudomonas aeruginosa is a leading cause of nosocomial infections. Increased resistance in this organism continues to cause a significant threat to patient care because of limited therapeutic options. Knowledge of the prevalence of P. aeruginosa in various infections and its antimicrobial susceptibility pattern is one of the salient attributes for selection of appropriate therapy.

Objective: To determine the prevalence and antibiotic resistance pattern of P. aeruginosa from various clinical samples collected from different ICUs.

Methodology: From 10,332 clinical specimen received over a period of one year, a total of 267 P. aeruginosa isolates were identified and minimum inhibitory concentrations for various antibiotics was found out with help of automated method VITEK 2 (bioMerieux).

Results: A total of 267 (2.58%) P. aeruginosa isolates were identified from various clinical specimens. Maximum number 49 (18.35%) of isolates were recovered from patients in 61-70 years age group. The sensitivity pattern of the isolates is as follows - colistin (80.14%), amikacin (52.05%), ciprofloxacin (47.19%), gentamicin (46.55%), cefepime (44.56%), imipenem (42.69%), cefoperazone/ sulbactam (42.69%), levofloxacin (41.57%), meropenem (39.70%), ceftazidime (38.20%), piperacillin/ tazobactam (31.08%), aztreonam (25.46%) and Ticarcillin/ clavulanic acid (22.47%).

Conclusion: The prevalence and sensitivity of P. aeruginosa varies between communities, hospitals and different patient populations. It is therefore, important to institute a system of surveillance in a hospital so that clinicians have access to recent data on prevalence and antimicrobial resistance which helps in making clinical judgement in therapy.


Keywords: antibiogram; Pseudomonas aeruginosa; ICU setting