Carcinoma of sphenoid sinus in young individual - Case report

Subrahmanyam C, Vijayan A, Amarnath SB, Mohammad K, Kumar S, Sudhakar P

Pdf Page Numbers :- 243-247

Subrahmanyam C^1,*, Anjali Vijayan¹, Amarnath SB², Kasif Mohammad³, Siva Kumar⁴ and Pushpalata Sudhakar⁵

¹Department of Otorhinolaryngology, Krishna Institute of Medical Sciences (KIMS), Secunderabad-500003, Telangana, India

²Department of Otorhinolaryngology, SVIMS-Sri Padmavathi Medical College for Women, Tirupati, Andhra Pradesh-517507, India

³Department of Pathology, Krishna Institute of Medical Sciences (KIMS), Secunderabad-500003, Telangana, India

⁴Department of Radiation Oncology, Krishna Institute of Medical Sciences (KIMS), Secunderabad-500003, Telangana, India

⁵Department of Nuclear Medicine, Krishna Institute of Medical Sciences (KIMS), Secunderabad-500003, Telangana, India

*Corresponding author: Dr. C. Subhramanyam, MS, ENT (PGI, Chandigarh), Consultant surgeon, Department of Otorhinolaryngology, Krishna Institute of Medical Sciences (KIMS), Secunderabad-500003, Telangana, India. Email: drcsubrahmanyam@gmail.com

Received 16 July 2022; Revised 2 September 2022; Accepted 10 September 2022; Published 16 September 2022

Citation: Subrahmanyam C, Vijayan A, Amarnath SB, Mohammad K, Kumar S, Sudhakar P. Carcinoma of sphenoid sinus in young individual - Case report. J Med Sci Res. 2022; 10(4):243-247. DOI: http://dx.doi.org/10.17727/JMSR.2022/10-45

Copyright: © 2022 Subrahmanyam C et al. Published by KIMS Foundation and Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Abstract

Neoplasms of paranasal sinuses account for 0.2-0.8% of all cancers and for 2-3% of head and neck cancers. Primary involvement of sphenoidal sinus is very rare and has been reported to occur only in 1-2% of all paranasal sinus tumors. Unlike neoplasms of other paranasal sinuses, tumors of sphenoid sinus most commonly cause headache, visual disturbances and cranial neuropathies. The most common histological types reported include squamous cell carcinoma, adenocarcinoma, adenoid cystic carcinoma and lymphoma. We describe a case of 17-years-old male who presented with headache and difficulty in eye movements. Magnetic resonance contrast study showed an enhancing mass in sphenoid sinus infiltrating to cavernous sinus. Endoscopic intranasal biopsy was done. The histological diagnosis was poorly differentiated squamous cell carcinoma. He underwent chemoradiation. While undergoing treatment his vision got deteriorated. Follow-up Magnetic resonance imaging revealed intracranial and intraorbital extension of disease. The purpose of presenting this case report is that very few cases are reported in the world literature so far of sphenoid malignancy in this age group.

Keywords: sphenoid; sinus; carcinoma; young individual