Gallbladder cancer in eastern India – The current scenario and the challenges for the future

Mallick SK, Nahid G, Deb AR

Pdf Page Numbers :- 87-92

Swapan Kumar Mallick^1,*, Gufran Nahid² and Asit Ranjan Deb³

¹Department of Radiotherapy, Malda Medical College, West Bengal University of Health Science, West Bengal-700064, India

²Department of Radiotherapy, North Bengal Medical College Kolkata, West Bengal University of Health Science, West Bengal-700064, India 3Department of Radiotherapy, Medical College Kolkata, West Bengal University of Health Science, West Bengal-700064, India

*Corresponding author: Dr. Swapan Kumar Mallick, Department of Radiotherapy, Malda Medical College, West Bengal University of Health Science, West Bengal-700064, India. Email: dr.skmallick@gmail.com

Received 11 January 2022; Revised 8 March 2022; Accepted 16 March 2022; Published 24 March 2022

Citation: Mallick SK, Nahid G, Deb AR. Gallbladder cancer in eastern India – The current scenario and the challenges for the future. J Med Sci Res. 2022; 10(2):87-92. DOI: http://dx.doi.org/10.17727/JMSR.2022/10-17

Copyright: © 2022 Mallick SK et al. Published by KIMS Foundation and Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Abstract

Background: The incidence of gallbladder cancer is high in our institute. In India, there is lack of epidemiological study to identify putative risk factors causing gallbladder carcinoma. This study was designed to observe clinical, epidemiological aspects and risk factor of the gallbladder cancer. Early detection and diagnosis will help to decrease gallbladder carcinoma related mortality.

Material and methods: After obtaining institutional ethics committee approval, gallbladder cases were identified from the institutional cancer registry. Then those data were tabulated in the excel sheet in the different epidemiological parameters and its outcome responses during June 2019 to December 2020.

Results: Among 108 patients gallbladder adenocarcinoma were predominant (89.81%) followed by squamous cell carcinoma (10.19%). Most patients were female (64%) with metastatic presentation (86%). Most commonly encountered risk factors were Gall stone disease (59.26%). 11% patients with porcelain gallbladder causing gallbladder carcinoma were found in this study.

Conclusion: The incidence has been on a steady rise in Indian population. The presentation is often with advanced disease and carries dismal prognosis. Most of the patient presented late, due to disease remain silent in early stage and also delayed and few were irregular in follow-up due to COVID-19 pandemic. Further studies with longer duration of follow-up are necessary.

Keywords: incidence; hepatitis B & C virus; gallbladder cancer; gallbladder stone