Volume : 5
Issue : 4
Rare case of recurrent Kikuchi-Fujimoto disease
Sarath Chandra Mouli Veeravalli, Suvarna Shilpa S, Satish Rao I, Prathibha B
Pdf Page Numbers :- 135-138
Sarath Chandra Mouli Veeravalli1,*, Suvarna Shilpa S1, Satish Rao I2 and Prathibha B1
1Department of Rheumatology and clinical Immunology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, India
2Department of Pathology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, India
*Corresponding author: Sarath Chandra Mouli Veeravalli, Clinical Director, Department of Rheumatology and Clinical Immunology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, India. Email: firstname.lastname@example.org
Received 15 July 2017; Revised 21 August 2017; Accepted 05 September 2017; Published 15 September 2017
Citation: Veeravalli SCM, SS, Satishrao I, Prathibha B. Rare case of recurrent Kikuchi-Fujimoto disease. J Med Sci Res. 2017; 5(4):135-138. DOI: http://dx.doi.org/10.17727/JMSR.2017/5-25
Copyright: © 2017 Veeravalli SCM, et al. Published by KIMS Foundation and Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Kikuchi-Fujimoto disease (KFD), or histiocytic necrotizing lymphadenitis, is a rare benign, self-limiting cervical lymphadenitis of unknown etiology. It closely mimics infective and immunological disorders. Here a rare case of recurrent KFD in a 13-year-old girl is presented. This girl presented with low grade fever at night times with sweating of 20 days duration and with painful right cervical lymphadenopathy. She had a bad history of recurrent episodes of lymphadenopathy seven years ago again after two years ago she was treated with empirical ATT. Her routine blood and urine tests were normal. Tests for infection and autoimmunity were negative. Histopathological examination is suggestive of Kikuchi lymphadenitis. Thus, she was diagnosed as a case of recurrent Kikuchi and was treated with oral steroids and hydroxychloroquine (HCQ). To the best of our knowledge, this is the first case of recurrent Kikuchi observed in an Indian patient and treated with Hydroxychloroquine and low dose steroids.
Keywords: Kikuchi-Fujimoto disease; histiocytic necrotizing lymphadenitis; plasmacytoid dendritic cells; hydroxychloroquine