Imaging spectrum of osteogenesis imperfecta – Pictorial essay

Subbarao Kakarla

Pdf Page Numbers :- 109-114

Subbarao Kakarla^1,*

¹Chairman, KIMS Foundation and Research Centre, Minister Road, Secunderabad - 500003, Telangana, India

*Corresponding author: Prof. Kakarla Subbarao, MS, D.Sc. (HON), FRCR, FACR, FICP, FSASMA, FCCP, FICR, FCGP, Chairman, KIMS Foundation and Research Centre, Minister Road, Secunderabad - 500003, Telangana, India. Email: subbaraokakarla25@gmail.com

Received 2 July 2019; Revised 28 August 2019; Accepted 6 September 2019; Published 16 September 2019

Citation: Kakarla S. Imaging spectrum of osteogenesis imperfecta – Pictorial essay. J Med Sci Res. 2019; 7(4):109-114. DOI: http://dx.doi.org/10.17727/JMSR.2019/7-19

Copyright: © 2019 Kakarla S et al. Published by KIMS Foundation and Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Abstract

Osteogenesis imperfecta (OI) is a rare genetic disorder caused by the disturbance in the synthesis of Type I Collagen and is divided into several types. Severe form of OI, mainly type II can be diagnosed in utero by ultrasonography during the second trimester of pregnancy. All the other types viz. Type I to Type VIII are diagnosed by conventional radiography. Many authors have classified these into several types. This essay is not meant for a comprehensive review of these types. The main features include fractures, gracile bones, kypho scoliosis, deformities, and wormian bones in skull. These radiologic features are described pictorially.

Keywords: Osteogenesis Imperfecta; fragile bones; multiple fractures; osteopenia; pseudoarthrosis; wormian bones; hyperplastic callus