Standardized cytopathology reporting of fluids using newly proposed international system for reporting serous fluid cytology - A single institutional experience

Murugan R, Kandasamy S, Gunasekaran KP, Ramalingam GS, Kulandaivel AL

Pdf Page Numbers :- 220-225

Roopmala Murugan¹, Sangeetha Kandasamy², Kumudhini Priya Gunasekaran¹, Gowri Sankar Ramalingam^1,* and Anbu Lenin Kulandaivel³

¹Department of Pathology, Vinayaka Mission’s Kirupananda Variyar Medical College and Hospitals, Vinayaka Mission's Research Foundation (Deemed to be University), Salem, Tamil Nadu 636308, India

²Department of Pathology, St. Peter’s Medical College, Hospital and Research Institute, Hosur, Tamil Nadu 635109, India

³Department of Immunohematology and Blood Transfusion, Vinayaka Mission’s Kirupananda Variyar Medical College and Hospitals, Vinayaka Mission's Research Foundation (Deemed to be University), Salem, Tamil Nadu 636308, India

*Corresponding author: Dr. Gowri Sankar Ramalingam, Associate Professor, Department of Pathology, Vinayaka Mission’s Kirupananda Variyar Medical College and Hospitals, Vinayaka Mission's Research Foundation (Deemed to be University), Salem, Tamil Nadu 636308, India. Email: gowrishines@gmail.com

Received 16 March 2023; Revised 24 May 2023; Accepted 5 June 2023; Published 16 June 2023

Citation: Murugan R, Kandasamy S, Gunasekaran KP, Ramalingam GS, Kulandaivel AL. Standardized cytopathology reporting of fluids using newly proposed international system for reporting serous fluid cytology - A single institutional experience. J Med Sci Res. 2023; 11(3):220-225. DOI: http://dx.doi.org/10.17727/JMSR.2023/11-41

Copyright: © 2023 Murugan R et al. Published by KIMS Foundation and Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Abstract

Background: Serous fluids are commonly produced in many disease conditions and it is relatively easy to collect it. Subjecting it to analysis will help identify the etiology of the disease process and thereby help the clinicians to plan the treatment strategy appropriately. The application of the international system for reporting serous fluid cytology will further make it easy for the clinicians with its simpler terminologies and clear categorization of entities.

Materials and method: All effusion samples that were received from 2020 to 2022 were examined and categorized according to international system for reporting serous fluid cytology. Risk of malignancy (ROM) was also calculated.

Results: Among 400 cases, 140 (35%) were pleural fluid, 260 (65%) were ascitic fluid. Among 140 pleural fluid, 8 (5.7%) were ND, 121 (86.4%) were NFM, 2 (1.4%) were AUS, 5(3.6%) were SFM and 4 (2.9%) were MAL. Among the 260 peritoneal fluid, 13 (5%), 226 (86.9%), 9 (3.5%), 9 (3.5%), and 3 (1.1%) were reported as ND, NFM, AUS, SFM and MAL respectively. Risk of Malignancy (ROM) calculated for the cases collected in this study were 0% for ND, 0.9% for NFM, 45.5% for AUS, 71.4% for SFM and 100% for MAL.

Conclusion: The international system (TIS) for reporting serous fluid cytopathology is very easy to employ and gives high accuracy with clear diagnostic criteria for each category, hence makes it easy to communicate with the clinicians by employing simple terminologies.

Keywords: serous effusion; serous fluid; pleural effusion; peritoneal effusion; TIS