Assessment of hip and femur fractures in patients with chronic kidney disease: A clinical evaluation

Suryanarayana MSA, Rasquinha CJ, Vellingiri K, Shanmugam K, Sreeharin B

Pdf Page Numbers :- 206-210

Meenakshi S Andra Suryanarayana¹, Chetan J Rasquinha², Kishore Vellingiri^3,*, Karthikeyan Shanmugam⁴ and Baskaran Sreeharin¹

¹Department of Biochemistry, PSG institute of Medical Sciences and Research, Coimbatore, Tamil Nadu 641004, India

²Department of Orthopaedics, HOSMAT Hospital, Magrath Road, Bengaluru, Karnataka 560025, India

³Department of Orthopedics, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research, Kolar, Karnataka 563101, India

⁴Department of Community Medicine, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu 641004, India

*Corresponding author: Dr. Kishore Vellingiri, Department of Orthopedics, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research, Kolar, Karnataka 563101, India. Email: kishorembbs13@gmail.com

Received 16 December 2024; Revised 26 February 2025; Accepted 6 March 2025; Published 13 March 2025

Citation: Suryanarayana MSA, Rasquinha CJ, Vellingiri K, Shanmugam K, Sreeharin B. Assessment of hip and femur fractures in patients with chronic kidney disease: A clinical evaluation. J Med Sci Res. 2025; 13(2):206-210. DOI: http://dx.doi.org/10.17727/JMSR.2024/13-36

Copyright: © 2025 Suryanarayana MSA et al. Published by KIMS Foundation and Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Abstract

Introduction: Chronic kidney disease (CKD) is a progressive condition characterized by declining kidney function, which also impacts bone metabolism, particularly through vitamin D activation. Patients with CKD are at an increased risk of osteoporosis and delayed bone healing. This study aims to evaluate the relationship between CKD and clinical outcomes in patients with hip and femur fractures.

Materials and Methods: Serum creatinine and urea levels, along with RUSH and BMD scores, were analyzed in patients. Statistical analysis was performed to assess the correlation between these variables.

Results: Higher serum urea and creatinine levels were associated with lower BMD and RUSH scores, indicating poorer bone density and delayed healing. However, the correlation was weak.

Conclusion: Although kidney function markers such as creatinine and urea suggest a potential link with fracture healing outcomes, the relationship remains weak. Continuous monitoring of kidney function is essential in hospitalized patients, but further research with a larger sample size and comprehensive monitoring is needed to better understand fracture recovery in CKD patients.

Keywords: chronic kidney disease; hip fracture; femur fracture; creatinine; urea; BMD; RUSH